Method for Separation, Determination or Enrichment

专利名称：Method for Separation, Determination or

Enrichment of Different DNA Species

发明人：Dirk Osterloh,Karen Felsmann申请号：US14056756申请日：20131017

公开号：US20140127687A1公开日：20140508

摘要：The present invention relates to a method for separating, determining oraccumulating different DNA species that are present simultaneously in a sample, on thebasis of unmethylated CpG-dinucleotides occurring with different frequency, within eachDNA species present, wherein an unmethylated CpG motifs binding protein is

immobilized on a base material and the DNA bound to the immobilized protein is elutedusing an elution agent gradient, wherein specific concentration regions of the elutionagent used correlate with specific CpG-dinucleotide frequencies in the DNA speciespresent, so that during elution different fractions of DNA species are obtained that havedifferent frequencies of CpG-dinucleotides.

申请人：Analytik Jena AG

地址：Jena DE

国籍：DE

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