Novel human gene relating to respiratory diseases,

专利名称：Novel human gene relating to respiratory

diseases, obesity, and inflammatory boweldisease

发明人：Tim Keith,Randall D. Little,Paul Van

Eerdewegh,Josee Dupuis,Richard G. DelMastro,Jason Simon,Kristin Allen,Sunil Pandit

申请号：US10277216申请日：20021017

公开号：US20040002470A1公开日：20040101

专利附图：

摘要：This invention relates to genes identified from human chromosome 20p13-p12,which are associated with various diseases, including asthma. The invention also relates tothe nucleotide sequences of these genes, isolated nucleic acids comprising thesenucleotide sequences, and isolated polypeptides or peptides encoded thereby. Theinvention further relates to vectors and host cells comprising the disclosed nucleotidesequences, or fragments thereof, as well as antibodies that bind to the encodedpolypeptides or peptides. Also related are ligands that modulate the activity of thedisclosed genes or gene products. In addition, the invention relates to methods andcompositions employing the disclosed nucleic acids, polypeptides or peptides,

antibodies, and/or ligands for use in diagnostics and therapeutics for asthma and otherdiseases.

申请人：KEITH TIM,LITTLE RANDALL D.,EERDEWEGH PAUL VAN,DUPUIS JOSEE,DELMASTRO RICHARD G.,SIMON JASON,ALLEN KRISTIN,PANDIT SUNIL

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